Simultaneous Antagonism at H3R/D2R/D3R Reduces Autism-like Self-Grooming and Aggressive Behaviors by Mitigating MAPK Activation in Mice

Dysregulation in brain neurotransmitters underlies several neuropsychiatric disorders, e.g., autism spectrum disorder (ASD). Also, abnormalities in the extracellular-signal-regulated kinase (ERK)/mitogen-activated protein kinase (MAPK) pathway pave the way for neuroinflammation, neurodegeneration, a...

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Detalles Bibliográficos
Autores principales: Eissa, Nermin, Awad, Mohamed Al, Thomas, Shilu Deepa, Venkatachalam, Karthikkumar, Jayaprakash, Petrilla, Zhong, Sicheng, Stark, Holger, Sadek, Bassem
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9820264/
https://www.ncbi.nlm.nih.gov/pubmed/36613969
http://dx.doi.org/10.3390/ijms24010526

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9820264/
https://www.ncbi.nlm.nih.gov/pubmed/36613969
http://dx.doi.org/10.3390/ijms24010526

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