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Simultaneous Antagonism at H3R/D2R/D3R Reduces Autism-like Self-Grooming and Aggressive Behaviors by Mitigating MAPK Activation in Mice

Dysregulation in brain neurotransmitters underlies several neuropsychiatric disorders, e.g., autism spectrum disorder (ASD). Also, abnormalities in the extracellular-signal-regulated kinase (ERK)/mitogen-activated protein kinase (MAPK) pathway pave the way for neuroinflammation, neurodegeneration, a...

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Detalles Bibliográficos
Autores principales:	Eissa, Nermin, Awad, Mohamed Al, Thomas, Shilu Deepa, Venkatachalam, Karthikkumar, Jayaprakash, Petrilla, Zhong, Sicheng, Stark, Holger, Sadek, Bassem
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9820264/ https://www.ncbi.nlm.nih.gov/pubmed/36613969 http://dx.doi.org/10.3390/ijms24010526

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