Genome Editing Using Cas9 Ribonucleoprotein Is Effective for Introducing PDGFRA Variant in Cultured Human Glioblastoma Cell Lines

Many variants of uncertain significance (VUS) have been detected in clinical cancer cases using next-generation sequencing-based cancer gene panel analysis. One strategy for the elucidation of VUS is the functional analysis of cultured cancer cell lines that harbor targeted gene variants using genom...

Descripción completa

Detalles Bibliográficos
Autores principales: Hamada, Taiji, Yokoyama, Seiya, Akahane, Toshiaki, Matsuo, Kei, Tanimoto, Akihide
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9820287/
https://www.ncbi.nlm.nih.gov/pubmed/36613947
http://dx.doi.org/10.3390/ijms24010500

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9820287/
https://www.ncbi.nlm.nih.gov/pubmed/36613947
http://dx.doi.org/10.3390/ijms24010500

Ejemplares similares