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Characterization of a Novel Amphiphilic Cationic Chlorin Photosensitizer for Photodynamic Applications

A novel amphiphilic cationic chlorin e(6) derivative was investigated as a promising photosensitizer for photodynamic therapy. Two cationic –N(CH(3))(3)(+) groups on the periphery of the macrocycle provide additional hydrophilization of the molecule and ensure its electrostatic binding to the mitoch...

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Detalles Bibliográficos
Autores principales: Gradova, Margarita A., Gradov, Oleg V., Lobanov, Anton V., Bychkova, Anna V., Nikolskaya, Elena D., Yabbarov, Nikita G., Mollaeva, Mariia R., Egorov, Anton E., Kostyukov, Alexey A., Kuzmin, Vladimir A., Khudyaeva, Irina S., Belykh, Dmitry V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9820311/
https://www.ncbi.nlm.nih.gov/pubmed/36613788
http://dx.doi.org/10.3390/ijms24010345