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Snapshots of ABCG1 and ABCG5/G8: A Sterol’s Journey to Cross the Cellular Membranes

The subfamily-G ATP-binding cassette (ABCG) transporters play important roles in regulating cholesterol homeostasis. Recent progress in the structural data of ABCG1 and ABCG5/G8 disclose putative sterol binding sites that suggest the possible cholesterol translocation pathway. ABCG1 and ABCG5/G8 sha...

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Detalles Bibliográficos
Autores principales: Rezaei, Fatemeh, Farhat, Danny, Gursu, Gonca, Samnani, Sabrina, Lee, Jyh-Yeuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9820320/
https://www.ncbi.nlm.nih.gov/pubmed/36613930
http://dx.doi.org/10.3390/ijms24010484