Metal Complexes of a 5-Nitro-8-Hydroxyquinoline-Proline Hybrid with Enhanced Water Solubility Targeting Multidrug Resistant Cancer Cells

Multidrug resistance (MDR) in cancer is one of the major obstacles of chemotherapy. We have recently identified a series of 8-hydroxyquinoline Mannich base derivatives with MDR-selective toxicity, however with limited solubility. In this work, a novel 5-nitro-8-hydroxyquinoline-proline hybrid and it...

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Detalles Bibliográficos
Autores principales: Pivarcsik, Tamás, Pósa, Vivien, Kovács, Hilda, May, Nóra V., Spengler, Gabriella, Pósa, Szonja P., Tóth, Szilárd, Nezafat Yazdi, Zeinab, Özvegy-Laczka, Csilla, Ugrai, Imre, Szatmári, István, Szakács, Gergely, Enyedy, Éva A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9820345/
https://www.ncbi.nlm.nih.gov/pubmed/36614037
http://dx.doi.org/10.3390/ijms24010593

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9820345/
https://www.ncbi.nlm.nih.gov/pubmed/36614037
http://dx.doi.org/10.3390/ijms24010593

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