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Organ Weights in NPC1 Mutant Mice Partly Normalized by Various Pharmacological Treatment Approaches

Niemann-Pick Type C1 (NPC1, MIM 257220) is a rare, progressive, lethal, inherited autosomal-recessive endolysosomal storage disease caused by mutations in the NPC1 leading to intracellular lipid storage. We analyzed mostly not jet known alterations of the weights of 14 different organs in the BALB/c...

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Detalles Bibliográficos
Autores principales: Antipova, Veronica, Steinhoff, Lisa-Marie, Holzmann, Carsten, Rolfs, Arndt, Hempel, Carlos Junior, Witt, Martin, Wree, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9820376/
https://www.ncbi.nlm.nih.gov/pubmed/36614015
http://dx.doi.org/10.3390/ijms24010573