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Functional Heterodimerization between the G Protein-Coupled Receptor GPR17 and the Chemokine Receptors 2 and 4: New Evidence

GPR17, a G protein-coupled receptor, is a pivotal regulator of myelination. Its endogenous ligands trigger receptor desensitization and downregulation allowing oligodendrocyte terminal maturation. In addition to its endogenous agonists, GPR17 could be promiscuously activated by pro-inflammatory oxys...

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Detalles Bibliográficos
Autores principales: Daniele, Simona, Saporiti, Simona, Capaldi, Stefano, Pietrobono, Deborah, Russo, Lara, Guerrini, Uliano, Laurenzi, Tommaso, Ataie Kachoie, Elham, Palazzolo, Luca, Russo, Vincenzo, Abbracchio, Maria Pia, Eberini, Ivano, Trincavelli, Maria Letizia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9820414/
https://www.ncbi.nlm.nih.gov/pubmed/36613703
http://dx.doi.org/10.3390/ijms24010261