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Functional Heterodimerization between the G Protein-Coupled Receptor GPR17 and the Chemokine Receptors 2 and 4: New Evidence
GPR17, a G protein-coupled receptor, is a pivotal regulator of myelination. Its endogenous ligands trigger receptor desensitization and downregulation allowing oligodendrocyte terminal maturation. In addition to its endogenous agonists, GPR17 could be promiscuously activated by pro-inflammatory oxys...
Autores principales: | Daniele, Simona, Saporiti, Simona, Capaldi, Stefano, Pietrobono, Deborah, Russo, Lara, Guerrini, Uliano, Laurenzi, Tommaso, Ataie Kachoie, Elham, Palazzolo, Luca, Russo, Vincenzo, Abbracchio, Maria Pia, Eberini, Ivano, Trincavelli, Maria Letizia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9820414/ https://www.ncbi.nlm.nih.gov/pubmed/36613703 http://dx.doi.org/10.3390/ijms24010261 |
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