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Hispolon Methyl Ether, a Hispolon Analog, Suppresses the SRC/STAT3/Survivin Signaling Axis to Induce Cytotoxicity in Human Urinary Bladder Transitional Carcinoma Cell Lines

Bladder cancer is a leading human malignancy worldwide. Signal transducer and activator of transcription (STAT) 3 is an oncogenic transcription factor commonly hyperactivated in most human cancers, including bladder cancer. Notably, preclinical evidence has validated STAT3 blockade as a promising th...

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Detalles Bibliográficos
Autores principales: Kuo, Min-Yung, Yang, Wei-Ting, Ho, Yann-Jen, Chang, Ge-Man, Chang, Hsiung-Hao, Hsu, Chao-Yu, Chang, Chia-Che, Chen, Yi-Hsin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9820424/
https://www.ncbi.nlm.nih.gov/pubmed/36613579
http://dx.doi.org/10.3390/ijms24010138