Cargando…

Lineage Reconstruction of In Vitro Identified Antigen-Specific Autoreactive B Cells from Adaptive Immune Receptor Repertoires

The emergence, survival, growth and maintenance of autoreactive (AR) B-cell clones, the hallmark of humoral autoimmunity, leave their footprints in B-cell receptor repertoires. Collecting IgH sequences related to polyreactive (PR) ones from adaptive immune receptor repertoire (AIRR) datasets make th...

Descripción completa

Detalles Bibliográficos
Autores principales: Blazso, Peter, Csomos, Krisztian, Tipton, Christopher M., Ujhazi, Boglarka, Walter, Jolan E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9820449/
https://www.ncbi.nlm.nih.gov/pubmed/36613668
http://dx.doi.org/10.3390/ijms24010225