Trypanosoma brucei rhodesiense Inhibitor of Cysteine Peptidase (ICP) Is Required for Virulence in Mice and to Attenuate the Inflammatory Response

The protozoan Trypanosoma brucei rhodesiense causes Human African Trypanosomiasis, also known as sleeping sickness, and penetrates the central nervous system, leading to meningoencephalitis. The Cathepsin L-like cysteine peptidase of T. b. rhodesiense has been implicated in parasite penetration of t...

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Detalles Bibliográficos
Autores principales: Costa, Tatiana F. R., Goundry, Amy, Morrot, Alexandre, Grab, Dennis J., Mottram, Jeremy C., Lima, Ana Paula C. A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9820468/
https://www.ncbi.nlm.nih.gov/pubmed/36614101
http://dx.doi.org/10.3390/ijms24010656

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9820468/
https://www.ncbi.nlm.nih.gov/pubmed/36614101
http://dx.doi.org/10.3390/ijms24010656

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