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Trypanosoma brucei rhodesiense Inhibitor of Cysteine Peptidase (ICP) Is Required for Virulence in Mice and to Attenuate the Inflammatory Response
The protozoan Trypanosoma brucei rhodesiense causes Human African Trypanosomiasis, also known as sleeping sickness, and penetrates the central nervous system, leading to meningoencephalitis. The Cathepsin L-like cysteine peptidase of T. b. rhodesiense has been implicated in parasite penetration of t...
Autores principales: | Costa, Tatiana F. R., Goundry, Amy, Morrot, Alexandre, Grab, Dennis J., Mottram, Jeremy C., Lima, Ana Paula C. A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9820468/ https://www.ncbi.nlm.nih.gov/pubmed/36614101 http://dx.doi.org/10.3390/ijms24010656 |
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