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Inhibitors of the Sialidase NEU3 as Potential Therapeutics for Fibrosis

Fibrosing diseases are a major medical problem, and are associated with more deaths per year than cancer in the US. Sialidases are enzymes that remove the sugar sialic acid from glycoconjugates. In this review, we describe efforts to inhibit fibrosis by inhibiting sialidases, and describe the follow...

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Detalles Bibliográficos
Autores principales: Karhadkar, Tejas R., Chen, Wensheng, Pilling, Darrell, Gomer, Richard H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9820515/
https://www.ncbi.nlm.nih.gov/pubmed/36613682
http://dx.doi.org/10.3390/ijms24010239