Lactate Rewrites the Metabolic Reprogramming of Uveal Melanoma Cells and Induces Quiescence Phenotype

Uveal melanoma (UM), the most common primary intraocular cancer in adults, is among the tumors with poorer prognosis. Recently, the role of the oncometabolite lactate has become attractive due to its role as hydroxycarboxylic acid receptor 1 (HCAR1) activator, as an epigenetic modulator inducing lys...

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Detalles Bibliográficos
Autores principales: Longhitano, Lucia, Giallongo, Sebastiano, Orlando, Laura, Broggi, Giuseppe, Longo, Antonio, Russo, Andrea, Caltabiano, Rosario, Giallongo, Cesarina, Barbagallo, Ignazio, Di Rosa, Michelino, Giuffrida, Rosario, Parenti, Rosalba, Li Volti, Giovanni, Vicario, Nunzio, Tibullo, Daniele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9820521/
https://www.ncbi.nlm.nih.gov/pubmed/36613471
http://dx.doi.org/10.3390/ijms24010024

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9820521/
https://www.ncbi.nlm.nih.gov/pubmed/36613471
http://dx.doi.org/10.3390/ijms24010024

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