Investigation of the Fuzzy Complex between RSV Nucleoprotein and Phosphoprotein to Optimize an Inhibition Assay by Fluorescence Polarization

The interaction between Respiratory Syncytial Virus phosphoprotein P and nucleoprotein N is essential for the formation of the holo RSV polymerase that carries out replication. In vitro screening of antivirals targeting the N-P protein interaction requires a molecular interaction model, ideally cons...

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Detalles Bibliográficos
Autores principales: Khodjoyan, Silva, Morissette, Deborha, Hontonnou, Fortune, Checa Ruano, Luis, Richard, Charles-Adrien, Sperandio, Olivier, Eléouët, Jean-François, Galloux, Marie, Durand, Philippe, Deville-Foillard, Stéphanie, Sizun, Christina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9820559/
https://www.ncbi.nlm.nih.gov/pubmed/36614009
http://dx.doi.org/10.3390/ijms24010569

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9820559/
https://www.ncbi.nlm.nih.gov/pubmed/36614009
http://dx.doi.org/10.3390/ijms24010569

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