Targeting DNA Methylation in Leukemia, Myelodysplastic Syndrome, and Lymphoma: A Potential Diagnostic, Prognostic, and Therapeutic Tool

DNA methylation represents a crucial mechanism of epigenetic regulation in hematologic malignancies. The methylation process is controlled by specific DNA methyl transferases and other regulators, which are often affected by genetic alterations. Global hypomethylation and hypermethylation of tumor s...

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Detalles Bibliográficos
Autores principales: Kalinkova, Lenka, Sevcikova, Aneta, Stevurkova, Viola, Fridrichova, Ivana, Ciernikova, Sona
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9820560/
https://www.ncbi.nlm.nih.gov/pubmed/36614080
http://dx.doi.org/10.3390/ijms24010633

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9820560/
https://www.ncbi.nlm.nih.gov/pubmed/36614080
http://dx.doi.org/10.3390/ijms24010633

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