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Targeting DNA Methylation in Leukemia, Myelodysplastic Syndrome, and Lymphoma: A Potential Diagnostic, Prognostic, and Therapeutic Tool
DNA methylation represents a crucial mechanism of epigenetic regulation in hematologic malignancies. The methylation process is controlled by specific DNA methyl transferases and other regulators, which are often affected by genetic alterations. Global hypomethylation and hypermethylation of tumor s...
Autores principales: | Kalinkova, Lenka, Sevcikova, Aneta, Stevurkova, Viola, Fridrichova, Ivana, Ciernikova, Sona |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9820560/ https://www.ncbi.nlm.nih.gov/pubmed/36614080 http://dx.doi.org/10.3390/ijms24010633 |
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