Novel Chiral Ru(II) Complexes as Potential c-myc G-quadruplex DNA Stabilizers Inducing DNA Damage to Suppress Triple-Negative Breast Cancer Progression

Currently, effective drugs for triple-negative breast cancer (TNBC) are lacking in clinics. c-myc is one of the core members during TNBC tumorigenesis, and G-rich sequences in the promoter region can form a G-quadruplex conformation, indicating that the c-myc inhibitor is a possible strategy to figh...

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Detalles Bibliográficos
Autores principales: Yuan, Chanling, Wang, Zhixiang, Wang, Zongtao, Liu, Wentao, Li, Guohu, Meng, Jinlan, Wu, Ruzhen, Wu, Qiong, Wang, Jiacheng, Mei, Wenjie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9820592/
https://www.ncbi.nlm.nih.gov/pubmed/36613647
http://dx.doi.org/10.3390/ijms24010203

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9820592/
https://www.ncbi.nlm.nih.gov/pubmed/36613647
http://dx.doi.org/10.3390/ijms24010203

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