The Difference in Zinc Concentrations Required for Induction among Metallothionein Isoforms Can Be Explained by the Different MTF1 Affinities to MREs in Its Promoter

Metallothioneins (MTs) are cysteine-rich low-molecular-weight proteins that protect cells from heavy metal toxicity. MT1 and MT2 are considered ubiquitously expressed among the MT isoforms ranging from 1 to 4. These MT1 and MT2 transcriptions are regulated by metal regulatory transcription factor 1...

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Detalles Bibliográficos
Autores principales: Ogushi, Shoko, Kimura, Tomoki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9820605/
https://www.ncbi.nlm.nih.gov/pubmed/36613726
http://dx.doi.org/10.3390/ijms24010283

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9820605/
https://www.ncbi.nlm.nih.gov/pubmed/36613726
http://dx.doi.org/10.3390/ijms24010283

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