Analgesic Action of Acetaminophen via Kv7 Channels

The mechanism of acetaminophen (APAP) analgesia is at least partially unknown. Previously, we showed that the APAP metabolite N-acetyl-p-benzoquinone imine (NAPQI) activated Kv7 channels in neurons in vitro, and this activation of Kv7 channels dampened neuronal firing. Here, the effect of the Kv7 ch...

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Detalles Bibliográficos
Autores principales: Stampf, Jan-Luca, Ciotu, Cosmin I., Heber, Stefan, Boehm, Stefan, Fischer, Michael J. M., Salzer, Isabella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9820628/
https://www.ncbi.nlm.nih.gov/pubmed/36614094
http://dx.doi.org/10.3390/ijms24010650

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9820628/
https://www.ncbi.nlm.nih.gov/pubmed/36614094
http://dx.doi.org/10.3390/ijms24010650

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