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Analgesic Action of Acetaminophen via Kv7 Channels

The mechanism of acetaminophen (APAP) analgesia is at least partially unknown. Previously, we showed that the APAP metabolite N-acetyl-p-benzoquinone imine (NAPQI) activated Kv7 channels in neurons in vitro, and this activation of Kv7 channels dampened neuronal firing. Here, the effect of the Kv7 ch...

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Detalles Bibliográficos
Autores principales:	Stampf, Jan-Luca, Ciotu, Cosmin I., Heber, Stefan, Boehm, Stefan, Fischer, Michael J. M., Salzer, Isabella
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9820628/ https://www.ncbi.nlm.nih.gov/pubmed/36614094 http://dx.doi.org/10.3390/ijms24010650

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