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Hijacking Chemical Reactions of P450 Enzymes for Altered Chemical Reactions and Asymmetric Synthesis

Cytochrome P450s are heme-containing enzymes capable of the oxidative transformation of a wide range of organic substrates. A protein scaffold that coordinates the heme iron, and the catalytic pocket residues, together, determine the reaction selectivity and regio- and stereo-selectivity of the P450...

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Detalles Bibliográficos
Autores principales: Rajakumara, Eerappa, Saniya, Dubey, Bajaj, Priyanka, Rajeshwari, Rajanna, Giri, Jyotsnendu, Davari, Mehdi D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9820634/
https://www.ncbi.nlm.nih.gov/pubmed/36613657
http://dx.doi.org/10.3390/ijms24010214