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The Adaptability of Chromosomal Instability in Cancer Therapy and Resistance
Variation in chromosome structure is a central source of DNA damage and DNA damage response, together representinga major hallmark of chromosomal instability. Cancer cells under selective pressure of therapy use DNA damage and DNA damage response to produce newfunctional assets as an evolutionary me...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9820635/ https://www.ncbi.nlm.nih.gov/pubmed/36613695 http://dx.doi.org/10.3390/ijms24010245 |