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CXCL4-RNA Complexes Circulate in Systemic Sclerosis and Amplify Inflammatory/Pro-Fibrotic Responses by Myeloid Dendritic Cells

CXCL4 is an important biomarker of systemic sclerosis (SSc), an incurable autoimmune disease characterized by vasculopathy and skin/internal organs fibrosis. CXCL4 contributes to the type I interferon (IFN-I) signature, typical of at least half of SSc patients, and its presence is linked to an unfav...

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Detalles Bibliográficos
Autores principales: Pietraforte, Immacolata, Butera, Alessia, Gaddini, Lucia, Mennella, Anna, Palazzo, Raffaella, Campanile, Doriana, Stefanantoni, Katia, Riccieri, Valeria, Lande, Roberto, Frasca, Loredana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9820649/
https://www.ncbi.nlm.nih.gov/pubmed/36614095
http://dx.doi.org/10.3390/ijms24010653