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CXCL4-RNA Complexes Circulate in Systemic Sclerosis and Amplify Inflammatory/Pro-Fibrotic Responses by Myeloid Dendritic Cells
CXCL4 is an important biomarker of systemic sclerosis (SSc), an incurable autoimmune disease characterized by vasculopathy and skin/internal organs fibrosis. CXCL4 contributes to the type I interferon (IFN-I) signature, typical of at least half of SSc patients, and its presence is linked to an unfav...
Autores principales: | Pietraforte, Immacolata, Butera, Alessia, Gaddini, Lucia, Mennella, Anna, Palazzo, Raffaella, Campanile, Doriana, Stefanantoni, Katia, Riccieri, Valeria, Lande, Roberto, Frasca, Loredana |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9820649/ https://www.ncbi.nlm.nih.gov/pubmed/36614095 http://dx.doi.org/10.3390/ijms24010653 |
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