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Distinct Effects of Beta-Amyloid, Its Isomerized and Phosphorylated Forms on the Redox Status and Mitochondrial Functioning of the Blood–Brain Barrier Endothelium

The Alzheimer’s disease (AD)-associated breakdown of the blood–brain barrier (BBB) promotes the accumulation of beta-amyloid peptide (Aβ) in the brain as the BBB cells provide Aβ transport from the brain parenchyma to the blood, and vice versa. The breakdown of the BBB during AD may be caused by the...

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Detalles Bibliográficos
Autores principales: Petrovskaya, Aleksandra V., Tverskoi, Artem M., Barykin, Evgeny P., Varshavskaya, Kseniya B., Dalina, Alexandra A., Mitkevich, Vladimir A., Makarov, Alexander A., Petrushanko, Irina Yu.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9820675/
https://www.ncbi.nlm.nih.gov/pubmed/36613623
http://dx.doi.org/10.3390/ijms24010183