Liraglutide Counteracts Endoplasmic Reticulum Stress in Palmitate-Treated Hypothalamic Neurons without Restoring Mitochondrial Homeostasis

One feature of high-fat diet-induced neurodegeneration in the hypothalamus is an increased level of palmitate, which is associated with endoplasmic reticulum (ER) stress, loss of CoxIV, mitochondrial fragmentation, and decreased abundance of MC4R. To determine whether antidiabetic drugs protect agai...

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Detalles Bibliográficos
Autores principales: Griffin, Haven, Sullivan, Sarah C., Barger, Steven W., Phelan, Kevin D., Baldini, Giulia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9820707/
https://www.ncbi.nlm.nih.gov/pubmed/36614074
http://dx.doi.org/10.3390/ijms24010629

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9820707/
https://www.ncbi.nlm.nih.gov/pubmed/36614074
http://dx.doi.org/10.3390/ijms24010629

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