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Prediction of Drug Synergism between Peptides and Antineoplastic Drugs Paclitaxel, 5-Fluorouracil, and Doxorubicin Using In Silico Approaches

Chemotherapy is the main treatment for most early-stage cancers; nevertheless, its efficacy is usually limited by drug resistance, toxicity, and tumor heterogeneity. Cell-penetrating peptides (CPPs) are small peptide sequences that can be used to increase the delivery rate of chemotherapeutic drugs...

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Detalles Bibliográficos
Autores principales: Vale, Nuno, Pereira, Mariana, Santos, Joana, Moura, Catarina, Marques, Lara, Duarte, Diana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9820768/
https://www.ncbi.nlm.nih.gov/pubmed/36613510
http://dx.doi.org/10.3390/ijms24010069