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Prediction of Drug Synergism between Peptides and Antineoplastic Drugs Paclitaxel, 5-Fluorouracil, and Doxorubicin Using In Silico Approaches
Chemotherapy is the main treatment for most early-stage cancers; nevertheless, its efficacy is usually limited by drug resistance, toxicity, and tumor heterogeneity. Cell-penetrating peptides (CPPs) are small peptide sequences that can be used to increase the delivery rate of chemotherapeutic drugs...
Autores principales: | Vale, Nuno, Pereira, Mariana, Santos, Joana, Moura, Catarina, Marques, Lara, Duarte, Diana |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9820768/ https://www.ncbi.nlm.nih.gov/pubmed/36613510 http://dx.doi.org/10.3390/ijms24010069 |
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