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The MAOA rs979605 Genetic Polymorphism Is Differentially Associated with Clinical Improvement Following Antidepressant Treatment between Male and Female Depressed Patients

Major depressive disorder (MDD) is the leading cause of disability worldwide. Treatment with antidepressant drugs (ATD), which target monoamine neurotransmitters including serotonin (5HT), are only modestly effective. Monoamine oxidase (MAO) metabolizes 5HT to 5-hydroxy indoleacetic acid (5HIAA). Ge...

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Detalles Bibliográficos
Autores principales: Chappell, Kenneth, Colle, Romain, Bouligand, Jérôme, Trabado, Séverine, Fève, Bruno, Becquemont, Laurent, Corruble, Emmanuelle, Verstuyft, Céline
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9820795/
https://www.ncbi.nlm.nih.gov/pubmed/36613935
http://dx.doi.org/10.3390/ijms24010497