Murine Fibroblasts and Primary Hepatocytes as Tools When Studying the Efficacy of Potential Therapies for Mucopolysaccharidosis Type I

Mucopolysaccharidosis type I (MPS I) is a metabolic genetic disease caused by the deficiency of a lysosomal enzyme involved in glycosaminoglycans (GAGs) degradation. MPS I cells have a constant level of GAG synthesis, but disturbed degradation means that GAGs accumulate progressively, impairing cell...

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Detalles Bibliográficos
Autores principales: Węsierska, Magdalena, Nowicka, Wioletta, Kloska, Anna, Jakóbkiewicz-Banecka, Joanna, Malinowska, Marcelina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9820816/
https://www.ncbi.nlm.nih.gov/pubmed/36613977
http://dx.doi.org/10.3390/ijms24010534

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9820816/
https://www.ncbi.nlm.nih.gov/pubmed/36613977
http://dx.doi.org/10.3390/ijms24010534

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