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Expression and Function of StAR in Cancerous and Non-Cancerous Human and Mouse Breast Tissues: New Insights into Diagnosis and Treatment of Hormone-Sensitive Breast Cancer

Breast cancer (BC) is primarily triggered by estrogens, especially 17β-estradiol (E2), which are synthesized by the aromatase enzyme. While all steroid hormones are derived from cholesterol, the rate-limiting step in steroid biosynthesis is mediated by the steroidogenic acute regulatory (StAR) prote...

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Detalles Bibliográficos
Autores principales: Manna, Pulak R., Ramachandran, Sabarish, Pradeepkiran, Jangampalli Adi, Molehin, Deborah, Castro-Piedras, Isabel, Pruitt, Kevin, Ganapathy, Vadivel, Reddy, P. Hemachandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9820903/
https://www.ncbi.nlm.nih.gov/pubmed/36614200
http://dx.doi.org/10.3390/ijms24010758