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In Silico Identification and In Vitro Evaluation of New ABCG2 Transporter Inhibitors as Potential Anticancer Agents

Different molecular mechanisms contribute to the development of multidrug resistance in cancer, including increased drug efflux, enhanced cellular repair mechanisms and alterations of drug metabolism or drug targets. ABCG2 is a member of the ATP-binding cassette superfamily transporters that promote...

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Detalles Bibliográficos
Autores principales: Di Micco, Simone, Di Sarno, Veronica, Rossi, Martina, Vestuto, Vincenzo, Konno, Takumi, Novi, Sara, Tecce, Mario Felice, Napolitano, Valeria, Ciaglia, Tania, Vitale, Andrea, Gomez-Monterrey, Isabel Maria, Bifulco, Giuseppe, Bertamino, Alessia, Ostacolo, Carmine, Blasi, Paolo, Fasano, Alessio, Campiglia, Pietro, Musella, Simona
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9820944/
https://www.ncbi.nlm.nih.gov/pubmed/36614168
http://dx.doi.org/10.3390/ijms24010725