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Elucidating the Interaction between Pyridoxine 5′-Phosphate Oxidase and Dopa Decarboxylase: Activation of B6-Dependent Enzyme

Pyridoxal 5′-phosphate (PLP), the active form of vitamin B6, serves as a cofactor for scores of B6-dependent (PLP-dependent) enzymes involved in many cellular processes. One such B6 enzyme is dopa decarboxylase (DDC), which is required for the biosynthesis of key neurotransmitters, e.g., dopamine an...

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Detalles Bibliográficos
Autores principales: AL Mughram, Mohammed H., Ghatge, Mohini S., Kellogg, Glen E., Safo, Martin K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9820991/
https://www.ncbi.nlm.nih.gov/pubmed/36614085
http://dx.doi.org/10.3390/ijms24010642