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Proteome-Wide Structural Computations Provide Insights into Empirical Amino Acid Substitution Matrices
The relative contribution of mutation and selection to the amino acid substitution rates observed in empirical matrices is unclear. Herein, we present a neutral continuous fitness-stability model, inspired by the Arrhenius law ([Formula: see text]). The model postulates that the rate of amino acid s...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2023
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9821064/ https://www.ncbi.nlm.nih.gov/pubmed/36614247 http://dx.doi.org/10.3390/ijms24010796 |