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E3 Ubiquitin Ligase Midline 1 Regulates Endothelial Cell ICAM-1 Expression and Neutrophil Adhesion in Abdominal Sepsis

Septic lung damage is associated with endothelial cell and neutrophil activation. This study examines the role of the E3 ubiquitin ligase midline 1 (Mid1) in abdominal sepsis. Mid1 expression was increased in endothelial cells derived from post-capillary venules in septic mice and TNF-α challenge in...

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Detalles Bibliográficos
Autores principales: Du, Feifei, Hawez, Avin, Ding, Zhiyi, Wang, Yongzhi, Rönnow, Carl-Fredrik, Rahman, Milladur, Thorlacius, Henrik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9821100/
https://www.ncbi.nlm.nih.gov/pubmed/36614145
http://dx.doi.org/10.3390/ijms24010705