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Inhibition of Oncogenic Src Ameliorates Silica-Induced Pulmonary Fibrosis via PI3K/AKT Pathway

Silicosis is a refractory disease. Previous studies indicate that damaged alveolar epithelial cells act as a driver in pulmonary fibrosis. Our results show that epithelial cells that acquire the mesenchymal phenotype are associated with the pathogenesis of silicosis. c-Src kinase, a non-receptor tyr...

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Detalles Bibliográficos
Autores principales: Hao, Xiaohui, Jin, Yixuan, Zhang, Yiyang, Li, Shifeng, Cui, Jie, He, Hailan, Guo, Lingli, Yang, Fang, Liu, Heliang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9821169/
https://www.ncbi.nlm.nih.gov/pubmed/36614217
http://dx.doi.org/10.3390/ijms24010774