Conditional Knockout of Hypoxia-Inducible Factor 1-Alpha in Tumor-Infiltrating Neutrophils Protects against Pancreatic Ductal Adenocarcinoma

Large numbers of neutrophils infiltrate tumors and comprise a notable component of the inflammatory tumor microenvironment. While it is established that tumor cells exhibit the Warburg effect for energy production, the contribution of the neutrophil metabolic state to tumorigenesis is unknown. Here,...

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Detalles Bibliográficos
Autores principales: Sieow, Je Lin, Penny, Hweixian Leong, Gun, Sin Yee, Tan, Ling Qiao, Duan, Kaibo, Yeong, Joe Poh Sheng, Pang, Angela, Lim, Diana, Toh, Han Chong, Lim, Tony Kiat Hon, Engleman, Edgar, Rotzschke, Olaf, Ng, Lai Guan, Chen, Jinmiao, Tan, Suet Mien, Wong, Siew Cheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9821271/
https://www.ncbi.nlm.nih.gov/pubmed/36614196
http://dx.doi.org/10.3390/ijms24010753

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9821271/
https://www.ncbi.nlm.nih.gov/pubmed/36614196
http://dx.doi.org/10.3390/ijms24010753

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