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The Bivalent COVID-19 Booster Immunization after Three Doses of Inactivated Vaccine Augments the Neutralizing Antibody Response against Circulating Omicron Sublineages

A fourth dose of a COVID-19 vaccine has been recommended by a number of authorities due to waning immunity over time and the emergence of immune-escaping variants. Here, we evaluated the safety and immunogenicity of the bivalent BV-01-B5 or V-01D-351 or the prototype V-01 for heterologous boosting i...

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Detalles Bibliográficos
Autores principales: He, Qiaren, Sun, Shiyu, Chen, Xi, Hu, Zhenxiang, Zhang, Yan, Peng, Hua, Fu, Yang-Xin, Yang, Jiaming, Chen, Long
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9821285/
https://www.ncbi.nlm.nih.gov/pubmed/36614948
http://dx.doi.org/10.3390/jcm12010146