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The Inhibitory Properties of a Novel, Selective LMTK3 Kinase Inhibitor

Recently, the oncogenic role of lemur tyrosine kinase 3 (LMTK3) has been well established in different tumor types, highlighting it as a viable therapeutic target. In the present study, using in vitro and cell-based assays coupled with biophysical analyses, we identify a highly selective small molec...

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Detalles Bibliográficos
Autores principales: Agnarelli, Alessandro, Lauer Betrán, Andrea, Papakyriakou, Athanasios, Vella, Viviana, Samuels, Mark, Papanastasopoulos, Panagiotis, Giamas, Christina, Mancini, Erika J., Stebbing, Justin, Spencer, John, Cilibrasi, Chiara, Ditsiou, Angeliki, Giamas, Georgios
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9821308/
https://www.ncbi.nlm.nih.gov/pubmed/36614307
http://dx.doi.org/10.3390/ijms24010865