Association of Alpha-1 Antitrypsin Pi*Z Allele Frequency and Progressive Liver Fibrosis in Two Chronic Hepatitis C Cohorts

(1) Background: The inherited alpha-1 antitrypsin (A1AT) deficiency variant ‘Pi*Z’ emerged as a genetic modifier of chronic liver disease. Controversial data exist on the relevance of heterozygous Pi*Z carriage (‘Pi*MZ’ genotype) as an additional risk factor in patients with chronic viral hepatitis...

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Detalles Bibliográficos
Autores principales: Mücke, Victoria Therese, Fischer, Janett, Mücke, Marcus Maximilian, Teumer, Alexander, Koch, Alexander, Vermehren, Johannes, Fromme, Malin, Zeuzem, Stefan, Trautwein, Christian, Sarrazin, Christoph, Berg, Thomas, Zhou, Biaohuan, Hamesch, Karim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9821389/
https://www.ncbi.nlm.nih.gov/pubmed/36615054
http://dx.doi.org/10.3390/jcm12010253

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9821389/
https://www.ncbi.nlm.nih.gov/pubmed/36615054
http://dx.doi.org/10.3390/jcm12010253

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