Low doses of diarrhoeagenic E. coli induce enhanced monocyte and mDC responses and prevent development of symptoms after homologous rechallenge

The experimental challenge with attenuated enterotoxigenic E. coli strain E1392/75-2A prevents diarrhea upon a secondary challenge with the same bacteria. A dose-response pilot study was performed to investigate which immunological factors are associated with this protection. Healthy subjects were i...

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Detalles Bibliográficos
Autores principales: Porbahaie, Mojtaba, van den Belt, Maartje, Ulfman, Laurien, Ruijschop, Rianne M. A. J., Lucas–van de Bos, Elly, Hartog, Anita, Lenz, Stefanie, van Alen-Boerrigter, Ingrid J., Teodorowicz, Malgorzata, Savelkoul, Huub F. J., Calame, Wim, van Hoffen, Els, van Neerven, R. J. Joost, Kardinaal, Alwine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9821474/
https://www.ncbi.nlm.nih.gov/pubmed/36607972
http://dx.doi.org/10.1371/journal.pone.0279626

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9821474/
https://www.ncbi.nlm.nih.gov/pubmed/36607972
http://dx.doi.org/10.1371/journal.pone.0279626

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