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Elevated Circulating Lactate Levels and Widespread Expression of Its Cognate Receptor, Hydroxycarboxylic Acid Receptor 1 (HCAR1), in Ovarian Cancer

Background: Augmented glycolysis in cancer cells is a process required for growth and development. The Warburg effect provides evidence of increased glycolysis and lactic acid fermentation in cancer cells. The lactate end-product of glycolysis is receiving growing traction for its role as a cell sig...

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Detalles Bibliográficos
Autores principales: Kerslake, Rachel, Panfilov, Suzana, Mustafa, Nashrah, Hall, Marcia, Kyrou, Ioannis, Randeva, Harpal S., Karteris, Emmanouil, Godfrey, Richard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9821497/
https://www.ncbi.nlm.nih.gov/pubmed/36615018
http://dx.doi.org/10.3390/jcm12010217