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Elevated Circulating Lactate Levels and Widespread Expression of Its Cognate Receptor, Hydroxycarboxylic Acid Receptor 1 (HCAR1), in Ovarian Cancer
Background: Augmented glycolysis in cancer cells is a process required for growth and development. The Warburg effect provides evidence of increased glycolysis and lactic acid fermentation in cancer cells. The lactate end-product of glycolysis is receiving growing traction for its role as a cell sig...
Autores principales: | Kerslake, Rachel, Panfilov, Suzana, Mustafa, Nashrah, Hall, Marcia, Kyrou, Ioannis, Randeva, Harpal S., Karteris, Emmanouil, Godfrey, Richard |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9821497/ https://www.ncbi.nlm.nih.gov/pubmed/36615018 http://dx.doi.org/10.3390/jcm12010217 |
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