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Short-term carcinogenicity study of N-methyl-N-nitrosourea in FVB-Trp53 heterozygous mice

Carcinogenicity tests predict the tumorigenic potential of various substances in the human body by studying tumor induction in experimental animals. There is a need for studies that explore the use of FVB/N-Trp53(em2Hwl)/Korl (FVB-Trp53(+/-)) mice, created by TALEN-mediated gene targeting in Korea,...

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Detalles Bibliográficos
Autores principales: Kim, Na-Won, Seo, Sun-Min, Yoo, Eun-Seon, Kang, Ah-Reum, Lee, Ji-Hun, Lee, Jae-Hoon, Kang, Byeong-Cheol, Lee, Han-Woong, Choi, Yang-Kyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9821506/
https://www.ncbi.nlm.nih.gov/pubmed/36608059
http://dx.doi.org/10.1371/journal.pone.0280214