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Blockers of Skeletal Muscle Na(v)1.4 Channels: From Therapy of Myotonic Syndrome to Molecular Determinants of Pharmacological Action and Back

The voltage-gated sodium channels represent an important target for drug discovery since a large number of physiological processes are regulated by these channels. In several excitability disorders, including epilepsy, cardiac arrhythmias, chronic pain, and non-dystrophic myotonia, blockers of volta...

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Detalles Bibliográficos
Autores principales: De Bellis, Michela, Boccanegra, Brigida, Cerchiara, Alessandro Giovanni, Imbrici, Paola, De Luca, Annamaria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9821513/
https://www.ncbi.nlm.nih.gov/pubmed/36614292
http://dx.doi.org/10.3390/ijms24010857