Compressed Prostate Cancer Cells Decrease Osteoclast Activity While Enhancing Osteoblast Activity In Vitro

Once prostate cancer cells metastasize to bone, they perceive approximately 2 kPa compression. We hypothesize that 2 kPa compression stimulates the epithelial-to-mesenchymal transition (EMT) of prostate cancer cells and alters their production of paracrine signals to affect osteoclast and osteoblast...

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Detalles Bibliográficos
Autores principales: van Santen, Victor J. B., Zandieh Doulabi, Behrouz, Semeins, Cornelis M., Hogervorst, Jolanda M. A., Bratengeier, Cornelia, Bakker, Astrid D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9821660/
https://www.ncbi.nlm.nih.gov/pubmed/36614201
http://dx.doi.org/10.3390/ijms24010759

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9821660/
https://www.ncbi.nlm.nih.gov/pubmed/36614201
http://dx.doi.org/10.3390/ijms24010759

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