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Compressed Prostate Cancer Cells Decrease Osteoclast Activity While Enhancing Osteoblast Activity In Vitro

Once prostate cancer cells metastasize to bone, they perceive approximately 2 kPa compression. We hypothesize that 2 kPa compression stimulates the epithelial-to-mesenchymal transition (EMT) of prostate cancer cells and alters their production of paracrine signals to affect osteoclast and osteoblast...

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Detalles Bibliográficos
Autores principales:	van Santen, Victor J. B., Zandieh Doulabi, Behrouz, Semeins, Cornelis M., Hogervorst, Jolanda M. A., Bratengeier, Cornelia, Bakker, Astrid D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9821660/ https://www.ncbi.nlm.nih.gov/pubmed/36614201 http://dx.doi.org/10.3390/ijms24010759

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