Neurexin-2: An inhibitory neurexin that restricts excitatory synapse formation in the hippocampus

Neurexins are widely thought to promote synapse formation and to organize synapse properties. Here we found that in contrast to neurexin-1 and neurexin-3, neurexin-2 unexpectedly restricts synapse formation. In the hippocampus, constitutive or neuron-specific deletions of neurexin-2 nearly doubled t...

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Detalles Bibliográficos
Autores principales: Lin, Pei-Yi, Chen, Lulu Y., Jiang, Man, Trotter, Justin H., Seigneur, Erica, Südhof, Thomas C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2023
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9821874/
https://www.ncbi.nlm.nih.gov/pubmed/36608123
http://dx.doi.org/10.1126/sciadv.add8856

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9821874/
https://www.ncbi.nlm.nih.gov/pubmed/36608123
http://dx.doi.org/10.1126/sciadv.add8856

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